A deterministic method for estimating free energy genetic network landscapes with applications to cell commitment and reprogramming paths.

 Victor Olariu, Manesso Erica, Carsten Peterson, Royal Society Open Science.

2017;4(6):160765. doi:10.1098/rsos.160765

Different reprogramming propensities in plants and mammals: Are small variations in the core network wirings responsible?

Victor Olariu, Julia Nilsson, Henrik Jönsson, Carsten Peterson, PLoS One. 2017 Apr 6;12(4):e0175251. doi: 10.1371/journal.pone.0175251.

Nanog, Oct4 and Tet1 interplay in establishing pluripotency.

Victor Olariu, Cecilia Lövkvist, Kim Sneppen, Nature Scientific Reports, 2016; 6:25438 doi:10.1038/srep25438

 

A somatic mutation of GFI1B identified in leukemia alters cell fate via a SPI1 (PU.1) centered genetic regulatory network.

 Eduardo Anguita, Rajeev Gupta, Victor Olariu, Peter J. Valk, Carsten Peterson, Ruud Delwel, Tariq Enver, Developmental Biology, 2016, 411(2):277-286.

doi.org/10.1016/j.ydbio.2016.02.002

 

Stem Cells Dynamics - Naive Pluripotency and

Reprogramming

Victor Olariu, Open Access Biology London, 2014, 1(1):4 

Dynamic analysis of gene expression and genome-wide transcription factor binding during lineage-specific differentiation of multipotent progenitors.

 Gillian May, Shamit Soneji, Alex J. Tipping, Jose Teles, Simon McGowan, Mengchu Wu, Yanping Guo, Cristina Fugazza, John Brown, Cristina Pina, Victor Olariu, Steve Taylor, Daniel G. Tenen, Carsten Peterson, Tariq Enver, Cell Stem Cell, 2013, 13:6:754-768 doi: 10.1016/j.stem.2013.09.003

Probing the role of stochasticity in a model of the embryonic stem cell - heterogeneous gene expression and reprogramming efficiency.

 Vijay Chickarmane, Victor Olariu and Carsten Peterson, BMC Systems Biology, 2012, 6:98 doi:10.1186/1752-0509-6-98

Prepatterning in the Stem Cell Compartment

 Peter D. Tonge, Victor Olariu, Daniel Coca, Visakan Kadirkamanathan, Kelly E. Burrell, Stephen A. Billings, Peter W. Andrews PLoS ONE, 2010, 5(5): e10901. doi:10.1371/journal.pone.0010901

Modeling the evolution of culture-adapted human embryonic stem cells.

 Victor Olariu, S. Neil J. Harrison, Daniel Coca, Paul J. Gokhale, Duncan Baker, Steve Billings, Visakan Kadirkamanathan, Peter W. Andrews, Stem Cell Research, 2010, 4(1): 50-56 doi: 10.1016/j.scr.2009.09.001

Modeling Stem Cells Lineages with Markov Trees

 Victor Olariu, Daniel Coca, Stephen A. Billings and Visakan Kadirkamanathan, Pattern Recognition in Bioinformatics Lecture Notes in Computer Science, 5780, 2009, 233-243

Modified variational Bayes EM estimation of hidden Markov tree model of cell lineages.

Victor Olariu, Daniel Coca, Stephen A. Billings, Peter Tonge, Paul Gokhale, Peter W. Andrews and Visakan Kadirkamanathan, Bioinformatics, 2009, 25 (21): 2824-2830 doi: 10.1093/bioinformatics/btp456. 

Modelling the Expression of Marker Antigen SSEA3 for Embryonal Carcinoma Cells. Conference paper

Victor Olariu, Stephen A. Billings, Visakan Kadirkamanathan, Daniel Coca, P.

Tonge, P. Gokhale and P. W. Andrews, accepted at Foundation of Systems Biology in Engineering (FOSBE) conference at University of Stuttgart 2007.

Autonomous Mouse Embryonic Stem Cells and Reprogramming Efficiency Probing the Role of Stochasticity in a Minimal Mouse Stem Cell Architecture

Victor Olariu, Vijay Chickarmane and Carsten Peterson Conference proceedings paper accepted at International Society for Stem Cell Research 10th Annual Meeting, Yokohama, Japan 2012.

An Oct4-dependent gene regulatory network regulating epiblast and endoderm differentiation

 Victor Olariu, Hanna Peradziryi, Kim Sneppen, Josh Brickman Conference proceedings paper accepted at The Stem Cell Niche, Copenhagen, Denmark 2014

 

Stem cell gene networks dynamics governing epiblast and endoderm differentiation

Victor Olariu, Hanna Peradziryi, Kathryn Anderson, Josh Brickman, Kim Sneppen Conference proceeding paper accepted at Advanced Workshop on Interdisciplinary Views on Chromosome Structure and Function, Trieste, Italy 2014

Nanog, Oct4 and Tet1 interplay in establishing pluripotency

Victor Olariu, Cecilia Lovkvist, Kim Sneppen Conference proceedings paper accepted at International Society for Stem Cell Research 13th Annual Meeting Stockholm,

Sweden 2015.

Foreshadowing and execution of the transition from multipotency to commitment in individual early T-cell precursors.

 Ellen V Rothenberg, Wen Zhou, Mary A Yui, Xun Wang, Brian A Williams, Pawel Krupinski, Victor Olariu, Hao Yuan Kueh, Long Cai, Barbara J Wold, Carsten Peterson, Conference paper accepted at Single Cell Analyses Meeting, Cold Spring Harbor Laboratory, USA, 2017. 

Multi-scale dynamical modelling of early T-cell precursors commitment

Victor Olariu, Mary A. Yui, Pawel Krupinski, Wen Zhou, Ellen V Rothenberg, Carsten Peterson

5th International Synthetic & Systems Biology Summer School – SSBSS, Certosa di Pontignano - Siena, Tuscany, Italy, 2018

Journal Publications
Conference Proceedings Publications 

- George E. P. Box -

“All models are wrong.

Some are useful.”

PUBLICATIONS

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