My research is focused on developing useful computational models for transcriptional and

epigenetic circuitry inside the cells for understanding

cell decisions. 

My current interest is to propose original modelling 

techniques linked to  experimental data to elucidate 

mechanisms governing:

  • commitment of T-cell progenitors

  • direct conversion of adult fibroblast cells into neurones

  • reprogramming of mouse embryonic fibroblast cells into induced pluripotent stem (iPS) cells

Dr. Victor Olariu Annell

RECENT ARTICLES

Different reprogramming propensities in plants and mammals: Are small variations in the core network wirings responsible?
https://doi.org/10.1371/journal.pone.0175251
A deterministic method for estimating free energy genetic network landscapes with applications to cell commitment and reprogramming paths.
doi: 10.1098/rsos.160765
Nanog, Oct4 and Tet1 interplay in establishing pluripotency.
http://dx.doi.org/10.1038/srep25438
Teaching

 Systems Biology - Models and Computations FYTN12

Research
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